Alpha SMA Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Specification

Antigen	Alpha SMA
Concentration	0.35 mg/mL
Applications	Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Paraffin),Western Blot
Classification	Polyclonal
Conjugate	Unconjugated
Form	Liquid
Host Species	Rabbit
Regulatory Status	RUO
Target Species	Human,Mouse,Rat
Formulation	PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene Accession No.	P62736, P62737, P62738
Gene Alias	a SMA, AAT6, ACTA2, ACTA2 Smooth muscle Actin, ACTA2 Smooth muscle Actin Specific, Actin, aortic smooth muscle, Alpha actin 2, Alpha SMA, Alpha SMA Specific, a-SMA, smooth muscle actin, alpha SMA
Gene ID (Entrez)	11475, 59, 81633
Gene Symbols	ACTA2
Immunogen	Peptide
Isotype	IgG
Primary or Secondary	Primary
Purification Method	Antigen Affinity Chromatography
Content And Storage	-20°C
Product Type	Antibody
Gene	ACTA2

Among the six actin isoforms described in mammals, two are found in virtually all cells (b- and g-cytoplasmic), two are detected in smooth muscle cells (a- and g-smooth muscle) and two are present in striated muscles, one predomitly in skeletal (a-skeletal) and one in cardiac (a-cardiac) muscle cells. These actin isoforms differ slightly in their N-terminus and the sequences of each of them are perfectly conserved in higher vertebrates. Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells. In addition, it has also been shown to appear in stress fibers of fibroblastic cells during pathological situations involving contractile phenomena such as wound healing and fibrocontractive diseases.

Product Code	Brand	Quantity	Price	??product.searchResults.label.quantityAvail??	Quantity
16896595	Proteintech 55135-1-AP-20UL	20 μL	£135.0 20µL			Add to basket
16886595	Proteintech 55135-1-AP-150UL	150 μL	£349.0 150µL			Add to basket