Trimethylacetyl chloride, 98+%

Product Code. 11680212

Brand: Thermo Scientific Alfa Aesar A15051.AE

Description

CAS: 3282-30-2 | C5H9ClO | 120.58 g/mol

Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

Solubility
Miscible with acetonitrile.

Notes
Moisture sensitive. Incompatible withalcohols, oxidizing agents and strong bases.

Specifications

Chemical Identifiers

• CAS: 3282-30-2
• Molecular Formula: C5H9ClO
• Molecular Weight (g/mol): 120.58
• MDL Number: MFCD00000709
• InChI Key: JVSFQJZRHXAUGT-UHFFFAOYSA-N
• Synonym: pivaloyl chloride, trimethylacetyl chloride, propanoyl chloride, 2,2-dimethyl, pivalyl chloride, pivaloylchloride, 2,2-dimethylpropionyl chloride, pivalic acid chloride, pivalolyl chloride, unii-jq82j0o21t, 2,2-dimethylpropionylchloride
• PubChem CID: 62493
• IUPAC Name: 2,2-dimethylpropanoyl chloride
• SMILES: CC(C)(C)C(Cl)=O

• Melting Point: -57°C
• Density: 0.985
• Boiling Point: 105°C to 106°C
• Flash Point: 8°C (46°F)
• Odor: Pungent
• Refractive Index: 1.412
• Quantity: 100 mL
• UN Number: UN2438
• Beilstein: 385668
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with acetonitrile.
• Formula Weight: 120.58
• Percent Purity: ≥98%
• Chemical Name or Material: Trimethylacetyl chloride

Säkerhet och hantering

Produktbeteckning

• Trimethylacetyl chloride

Signalord

• Danger

Riskkategorier

• Acute toxicity Category 2
• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 1
• Flammable liquid Category 2
• Substances and mixtures corrosive to metals Category 1
• Skin corrosion/irritation Category 1 B

Faroangivelser

• H225-Highly flammable liquid and vapour.
• H290-May be corrosive to metals.
• H302-Harmful if swallowed.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.
• H330-Fatal if inhaled.

Skyddsangivelse

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Kompletterande information

• MIXTURE LIST-Contains : Pivaloyl chloride

SDS

RUO – Research Use Only