SPAG5 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Specification

Antigen	SPAG5
Concentration	0.36 mg/mL
Applications	Immunohistochemistry (Paraffin),Western Blot,Immunofluorescence,Immunocytochemistry,Immunoprecipitation
Classification	Polyclonal
Conjugate	Unconjugated
Form	Liquid
Host Species	Rabbit
Regulatory Status	RUO
Target Species	Human
Formulation	PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.	Q96R06
Gene Alias	Astrin, DEEPEST, hMAP126, MAP126, SPAG5, sperm associated antigen 5
Gene ID (Entrez)	10615
Gene Symbols	SPAG5
Immunogen	SPAG5 Fusion Protein Ag6485
Isotype	IgG
Primary or Secondary	Primary
Purification Method	Antigen Affinity Chromatography
Content And Storage	-20°C
Product Type	Antibody
Gene	SPAG5

SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST or Astrin, is a 1,193 amino acid protein that is expressed at high levels in testis and at lower levels in liver, placenta, pancreas, colon and thymus. Localized specifically to spindle poles during prophase and throughout the spindle during metaphase and anaphase, SPAG5 is essential for proper spindle formation and is thought to be involved in the dynamic and functional regulation of mitotic spindles. Additionally, SPAG5 plays a role in sister chromatid cohesion and subsequent chromatid separation and, via its association with chromatids, is an important regulator of chromosome integrity. SPAG5 has a long stalk and a globular head domain through which if forms a homodimer that is characterized by aster-like structures. Upon DNA damage, SPAG5 may be phosphorylated by ATR or ATM.

Product Code	Brand	Quantity	Price	??product.searchResults.label.quantityAvail??	Quantity
16883514	Proteintech 14726-1-AP-20UL	20 μL	£135.0 20µL			Add to basket
16873514	Proteintech 14726-1-AP-150UL	150 μL	£349.0 150µL			Add to basket